Quinine Market

Global Quinine Market Forecast

• Global quinine market size (2022) worth around US$2.1 Bn likely to reach US$3.2 Bn by 2030
• Market valuation poised to expand at a CAGR of 6.5% over 2023 - 2030

Quick Report Digest

1. The market for quinine is driven by increasing public concern about health and rising health awareness among the populace.
2. During the projection period, a continued increase in tonic water consumption may propel the market for quinine.
3. In 2022, the 200mg category dominated the industry. With the 200 mg quinine, the malaria parasites that reside inside red blood cells are eliminated. The amount and duration of treatment are determined by your health status, the nation where you contracted malaria, any additional malaria medications you may be taking, and how you respond to treatment.
4. In terms of market share for quinine globally, the problematic leg cramps segment is anticipated to dominate. Quinine is mostly used to treat uncomfortable leg cramps. For many years, quinine in a dose of 200-300 mg was recommended to treat nocturnal leg cramps.
5. In 2022, the intramuscular administration category controlled the market. Growing demand for biosimilars and immunisations, an increase in the number of chronic diseases that require intramuscular drug administration, and the increased acceptance of drug administration due to its advantages all contribute to the expansion of the worldwide intramuscular injectors market.
6. The hospital category is highly prevalent in the market for quinine. Being a focal point for comprehensive medical services is a significant contributor to the hospital segment's popularity as the top market share holder in the quinine market.
7. The North American region is anticipated to account for the largest share of the global quinine market due to the high frequency of malaria and other diseases spread by mosquitoes in this area. Despite continued government efforts to control these diseases, the US, one of the most malarious nations, nonetheless experiences their effects.
8. The market for quinine is expanding in Asia Pacific due to rising patient desire for Quinine derivatives, increasing disposable income that improves affordability, and higher healthcare spending.

A Look Back and a Look Forward - Comparative Analysis

The primary driver of the market is the rising consumption of alcoholic beverages, including gin, vodka, and other different kinds of cocktails. Additionally, tonic water contains a significant amount of quinine, which lowers the risk of malaria and other conditions affecting the legs. Throughout the projected period, these therapeutic features are anticipated to drive market expansion.

The market witnessed staggered growth during the historical period 2018 - 2022. Due to rising disposable incomes and increased consumer knowledge of the benefits of mixing tonic water with alcohol to create flavoured alcoholic beverages, throughout the anticipated period, the industry is expected to expand steadily.  Due to the deployment of lockdowns in many nations and the adoption of social distance measures as a result of the epidemic of coronavirus disease (COVID-19), tonic water sales have increased online, increasing the demand for quinine.

With the growing number of big hypermarkets, supermarkets, and convenience store chains that have increased their e-commerce operations in response to rising internet usage and surging smartphone sales, the demand for alcoholic beverages will increase, driving the growth of the market. Due to the developing taste for luxury spirits, consumers are prepared to spend money on novel goods with distinctive personalities. As a result, a number of industry participants are concentrating on the launch of unique product versions with extra flavours.

Key Growth Determinants

• Increasing Demand for Tonic Water

Since tonic water contains quinine, it is widely consumed as a healthful beverage worldwide. Quinine is included in this tonic water in amounts of 83 milligrams per liter, giving it exceptional therapeutic qualities. A wide range of items with artificial sweeteners and flavours are currently available from market makers.

The beverage's medicinal properties are also driving global demand for tonic water. Tonic water is used to cure malaria due to its quinine component. Leg cramps are lessened, it relieves stress, it replaces alcohol, which lowers alcohol consumption, and because of the high sugar content, it gives you more energy. Quinine's market is expanding due to the rising global demand for tonic water.

• Rising Cases of Malaria

14 million new cases of malaria were recorded in 2020, and the number of occurrences and fatalities reported in the new WHO malaria report is at its highest level since 2012. The most recent WHO data on malaria reveals the greatest rates of infections and fatalities since 2012, with over 93 percent of those deaths happening in Africa among children under the age of five.

The parasite Plasmodium falciparum, which infects red blood cells and causes malaria, is treated with quinine. The medication either eliminates the parasite or stops it from multiplying. Thus, it is projected that the increased number of malaria patients will increase the demand for quinine.

• Rising Alcoholic Beverage Consumption

Some bitter alcoholic beverages and, to a lesser extent, flour confections both include quinine. Gin and tonic have gained popularity among drinkers all over the world and are commonly referred to as "G and T" in nations like the United States, Canada, the United Kingdom, Ireland, Australia, and New Zealand. In general, the tonic water to gin ratio in most recipes ranges from 1:1 to 1:3.

Over the projected term, it is anticipated that these trends will continue to be beneficial for the sector. This is attributable to developed economies like the US, and the UK consuming more expensive beer. Beer, wine, and black spirits are in greater demand, which is driving up sales of alcoholic beverages.

Additionally, it is anticipated that the popularity of pubs, taverns, and restaurants will further stimulate the expansion of alcoholic drinks during the projection period, increasing the demand for quinine. The main driver of the industry is the rising popularity of beer's distinctive flavours as digestive aids.

Major Growth Barriers

• Low Awareness Among Consumers

Quinine is advertised only as a mixer for alcoholic beverages, even though it can also be consumed as a soft drink. This, combined with a low consumer understanding of quinine's numerous uses, may serve as a barrier to the market's growth.

• Potential Health Issues Associated with Quinine Consumption

Fever, easy bruising, headaches, sudden discomfort in the chest, and vision impairments are a few health complications associated with quinine use. During the forecast period, health problems related to quinine intake may have a negative impact on the expansion of the worldwide quinine market.

Key Trends and Opportunities to Look at

1. Product Innovations

The primary element most likely to fuel the expansion of the global quinine market is ongoing product innovation. To boost their product sales, the key market players are always innovating their products in terms of ingredients, formulation, calorie content, packaging, and other elements.

It is also known to strengthen the growth of the quinine market when the components are optimised, such as by using quinine from naturally occurring sources and natural sweeteners in place of sugar. Manufacturers in the global quinine market are spending money on R&D to create new flavours that will attract a variety of consumer palates.

2. Rising Spending Power of Consumers

The increased disposable income of individuals as a result of industrialisation and economic progress is a factor that has contributed to the growth of quinine on a global scale. In addition, urbanisation brought about by industry has altered people's lifestyles. Alcoholic beverages like gin, vodka, and others are now more frequently consumed as a result of this.

In alcoholic drinks, tonic water is commonly incorporated as a blend. In addition, it is predicted that social media impact would lead to an increase in alcohol consumption globally, a rise in the popularity of private and workplace parties, and the idea that alcoholic beverages help people unwind mentally.

3. Expanding Cocktail Culture

Tonic water is frequently consumed either straight up or combined with alcoholic drinks and mocktails. Gin and whisky drinkers have grown to love tonic water as a mixer during the past few years. Tonic water sales at bars and restaurants have increased as a direct result of rising gin consumption and the introduction of new brands.

Analysts predict that boomers and millennials will control tonic water sales as more of them enjoy the cocktail culture. Thus, with the growing cocktail culture, the quinine sector will open up new opportunities in the coming period.

How Does the Regulatory Scenario Shape this Industry?

Quinine, a naturally occurring compound derived from the Cinchona tree's bark, is currently used as an antimalarial drug, a supplement to relieve leg cramps, and a flavouring for drinks like tonic water with bitter lemon. Given that the therapeutic efficacy of quinine ranges from 500 to 1,000 mg, the FDA in the United States has set a limit of 83 mg/L for tonic water. Due to its severe adverse effects, the FDA only currently approves quinine as a treatment for malaria, despite the fact that it is widely available as a supplement for leg cramps and in tonic water.

Regardless of level, the Food and Drug Regulations at the federal level currently allow the sale of oral dose forms of quinine without a prescription. The DSSC's recommendation for prescription status at specific dosages is not reflected in this general authorisation. Quinine will be added to Schedule F with a set strength level for oral dose forms as part of this proposal.

To safeguard customers who may be susceptible to negative responses, the European Commission has also introduced new guidelines regarding labeling caffeine and quinine in beverages and food.

Fairfield’s Rankig Board

Top Segments

1. 200mg Dose Dominant over 300mg Dose

The 200mg segment dominated the market in 2022. The usual dosage of quinine, which is used to treat malaria, is 200 mg. Although it is an off-label medicinal use, numerous medical studies have shown that it is successful in treating malaria.

The 200mg dose of quinine, which goes by the trade name D Quinine Sulphate, contains 1% of the active component. A number of pharmaceutical firms, including Novartis AG, and GlaxoSmithKline Pharmaceuticals, produce it.

Furthermore, the 300mg category is projected to experience the fastest market growth. A generic drug for the treatment of malaria has a dosage of 300mg.

Additionally, it is used as a preventative against malaria in individuals at risk, such as expectant mothers and young children under the age of five. Leg cramps can also be treated with them. A number of pharmaceutical companies produce the 300mg dose of quinine, which includes roughly 0.75% of the active component.

2. Problematic Leg Cramps - a Prominent Application Area

In 2022, the problematic leg cramps category dominated the industry. For many years, nocturnal leg cramps were treated with a dose of 200-300 mg of quinine. These typical idiopathic muscular cramps are widespread, especially in elderly people. Quinine may be beneficial by lengthening the muscle refractory period and decreasing motor end-plate activity.

The malaria category is anticipated to grow substantially throughout the projected period. A medication called quinine is used to treat malaria. When artesunate is not available, quinine is used to treat malaria caused by a strain of Plasmodium falciparum that is chloroquine-resistant.

The World Health Organization (WHO) no longer recommends quinine as a first-line treatment for malaria as of 2006 because other medications are similarly effective and have fewer adverse effects. They advise against using it unless artemisinins are unavailable.

3. Intramuscular Administration Preferred the Most

The intramuscular administration segment dominated the market in 2022. Technological developments, favourable reimbursements, government assistance, and the availability of generic autoinjectors have all been positively predicted to boost the development of the global sector for intramuscular administration.

It is projected that technological developments, a rise in investors as a result of the strong demand for biologics development, and unexplored potential in emerging markets would all lead to profitable growth opportunities.

The oral administration category is expected to experience the fastest growth within the forecast time frame. The increase in the global geriatric population is one of the major factors driving the oral administration industry's expansion.

The surge in demand for investments in pharmaceutical research and development, as well as the rise in demand for self-administration and home care services among consumers, are driving the sector’s expansion.

4. Hospitals Lead in Demand Generation

In 2022, the hospitals category led the market growth. This group predominates because so many specialised medical specialists and healthcare professionals are involved in diagnosis and treatment. The public is educated and made more aware of a variety of ailments and situations in hospitals.

Moreover, the clinic category is expected to grow fastest in the quinine market during the forecast period. One of the main causes of the expansion is the growing emphasis on the usage of RDTs for their rapid turnaround times, affordability, and accessibility.

Clinics typically have fewer patients than hospitals, allowing them to deliver appropriate antimalarial drugs more quickly, thus improving patient outcomes.

Regional Frontrunners

North America’s Quinine Market Contributes the Largest Revenue Share

The quinine adoption is anticipated to dominate in North America. The biggest markets for quinine in North America are the U.S. and Canada, which presents a great opportunity for the industry. Additionally, gin consumption is high in these two nations, which raises tonic water consumption.

An increase in the consumption of these spirits is fueling the region's demand for quinine. Since bartenders at pubs and bars began blending premium tonic water in top-tier spirit brands, the growing trend for cocktails in Canada has contributed to the development of super-premium drinks.

Additionally, socioeconomic variables like the development and use of alcoholic beverages, as well as the significant urbanisation in Canada, have a favourable effect on mixers like tonic water.

Asia Pacific All Set for a Significant Rise Through 2030

With the increasing number of product approvals and commercial launches that have propelled market expansion in this region since 2012, Asia Pacific is projected to experience the greatest growth rate. Demand will increase in the Asia Pacific area during the projected period as a result of researchers searching for next-generation antimalarial treatments as a result of growing resistance to chloroquine.

India's large population base, which has increased patient awareness of malaria and a rise in disorders that cause fever, will continue to fuel market expansion. In nations like India, China, and Indonesia, consumption of different types of spirits like gin, whisky, vodka, and rum has been gradually rising. The demand for quinine in the area is being driven by the increase in alcohol consumption overall.

Fairfield’s Competitive Landscape Analysis

Quinine is a concentrated market with fewer significant competitors present worldwide. To increase their global footprint, the major firms are launching new items and enhancing their distribution networks. In addition, Fairfield Market Research anticipates that during the next few years, there will be further market consolidation.

Who are the Leaders in Global Quinine Space?

• Aecochem Corp
• Haihang Industry Co. Ltd.
• Actavis
• Shreeji Pharma International
• Wockhardt
• Vital Labs
• Trademax Pharmaceuticals & Chemicals
• Van Wankum Ingredients
• Hangzhou Dayang Co. Ltd.
• IS Chemical Technology Ltd.
• Leocorno Enterprises
• Bickford & Sons
• Fever-Tree
• Schweppes
• Chempro Pharma Private Limited

Significant Company Developments

New Product Launches

• February 2022: Leocorno Enterprises has launched the Peer luxury tonic water brand. Anant Jangwal launched the company in 2016 and sells consumer brands in India, the UAE, and the United Kingdom. Peer's current product line includes normal Indian Tonic, Mint Tonic, Bitter Lemon Tonic and a tonic with no calories or sugar. In the next months, it will introduce four more flavours and expand into other beverage categories that provide healthy options.
• June 2022: Bickford & Sons, an iconic South Australian firm, has developed a new, unusual tonic water to spice up your basic G&T this season. Tonic water, which was newly released, is made with natural, high-quality ingredients such as carbonated water, quinine, and sugar or natural sweetener. They're accessible in all South African independent stores and on Sippify.
• June 2022: Fever-Tree has released Spanish Clementine Refreshingly Light Tonic Water, just in time for summer. According to the manufacturer, the tonic is "subtly sweet, fruity, and vibrant" and is made by combining spring water with hand-picked clementines from Valencia and Quinine from Central Africa.
• March 2022: Schweppes has introduced two new products: Grapefruit Slimline Tonic and three new taste options in a new 600ml glass bottle. The former was introduced in response to changing consumer drinking patterns, with the unique grapefruit flavour reflecting a preference for fresh, bright citrus flavours that are ideal for summer drinking.
• February 2020: Love Tonic, a new mixer brand, has emerged in the United Kingdom with quinine-free tonic water perfect for blending with gin, vodka, tequila, whisky, or rum. The beverage was created "to help uncover the true flavour of the spirit it is mixed with," according to the company. Love Tonic is currently available in the United Kingdom for £1.65 per 200ml bottle.

An Expert’s Eye

Demand and Future Growth

As per Fairfield’s Analysis, an increase in the prevalence of malaria, especially in underdeveloped countries, is driving the market. The rising demand for alcoholic beverages may result in a growth in demand for gin and bitter-flavoured beer, where tonic water is favoured in large quantities, increasing the need for quinine.

Furthermore, technological developments have greatly aided the growth and development of various quinine. However, the quinine market is expected to face considerable challenges because of low awareness of quinine benefits.

Supply Side of the Market

According to our analysis, the manufacturers present in the quinine market are focusing on enhancing the quinine capacities and benefits by proving its effectiveness in the problematic leg cramps category, which will help the patients suffering from the same to get some relief effectively and at a fast rate.

In the forecasted period, the USA will be the biggest producer and consumer of quinine due to the growing consumption of tonic water for various purposes. The amount of alcohol consumed in the United States per person has climbed over the last few decades, and in 2021, it will be 2.51 gallons, thus increasing the demand for tonic water in the region.

However, the non-approval of the FDA for the usage of quinine for medical purposes may impede market growth in that particular field. Along with this, India witnessed significant growth due to the rising import of quinine in the region. India is the world's largest importer of quinine and sources the majority of its supplies from Germany, the Congo, and the United States. As of August 2023, 2.1K shipments of quinine were imported into India by 116 importers from 153 suppliers.

Additionally, the growing cases of malaria in the underdeveloped countries of the Asia Pacific region are contributing significantly. As of 2020, there were about 750.25 thousand cases of malaria in Papua New Guinea. This is due to the underdeveloped medical sector of countries like Papua New Guinea, increasing the demand for quinine.

Global Quinine Market is Segmented as Below:

By Type:

• 200 mg
• 300 mg
• Other

By Application:

• Problematic Leg Cramps
• Malaria
• Other

By Administration:

• Oral Administration
• Intramuscular Administration
• Intravenous Administration
• Others

By End User:

• Hospitals
• Clinics
• Others

By Geographic Coverage:

• North America 
  • U.S. 
  • Canada 
• Europe 
  • Germany
  • U.K.
  • France
  • Italy
  • Turkey
  • Russia
  • Rest of Europe 
• Asia Pacific 
  • China
  • Japan
  • South Korea
  • India
  • Southeast Asia
  • Rest of Asia Pacific 
• Latin America 
  • Brazil 
  • Mexico 
  • Argentina
  • Rest of Latin America 
• Middle East & Africa  
  • GCC 
  • South Africa
  • Egypt
  • Nigeria
  • Rest of Middle East & Africa